PCNA Primary Antibody

Item Information
Catalog # Size/Concentration Price
10019 100μl $308.00
AliasesMGC8367; PCNA
Product OrderP
Entrez GeneID5111
FormulationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Liquid in PBS containing 50% glycerol and 0.03% sodium azide.
ImmunogenSynthesized peptide derived from internal of human PCNA.
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C.  Learn More
Species ReactivityHuman, Mouse, Rat
IHC_P (Immunohistochemistry) 1/200 - 1/1000

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Western Blot

Cell Culture Products
Figure 1: Western blot analysis using PCNA Rabbit pAb against HepG2 (1) cell lysate.

Immunohistochemical analysis

Cell Culture Products
Figure 2: Immunohistochemical analysis of paraffin-embedded lung cancer (left), esophagus cancer tissues (right) using PCNA Rabbit pAb with DAB staining.
Product Overview
Description The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
References (references)
References (references) 1. Cell. 2010 Jan 8;140(1):123-35.
2. Cancer Invest. 2010 Jul;28(6):635-41.

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