By genetically engineering macrophages to express a CAR, it allows the macrophage the ability to recognize cancer cells more effectively, targeting specific antigens and thus triggering phagocytosis. Additionally, macrophages are able to directly present antigens to helper T-cells once they are activated and stimulate further response from the immune system.
Our custom development service for CAR-macrophages can be used to study the interaction of CAR-macrophages within the tumor micro-environment and study different agents (antibodies, cytokines, small molecules, etc). Our custom development package has been established for you to take direct advantage of our knowledge and platform.
ProMab can help you advance your ideas and technologies with two different plans: