We have plans that include monoclonal antibody development or are based on using your existing antibody sequence to generate the CAR constructs. When client requires antibody developed then Plan A is available starting at $22,500. When client provides antibody sequence Plan B starts at $16,950.
Plan A - Client receives 2 clones of hybridoma cell lines along with 2 x 108 CAR-NK cells cryopreserved.
Plan B - Client receives 2 x 108 CAR-NK cells cryopreserved.



Service Plans and Prices
PLAN A
DEVELOPMENT STAGE | DESCRIPTION | Price |
---|---|---|
Phase I (optional) | Immunization of Balb/C mice with recombinant protein or carrier-conjugated peptide. Generation of hybridoma cell lines following antibody validation against the correctly-presented antigen. | $5,150 |
Phase II (optional) | Sequencing of the antibody's heavy and light chains. | $1,600 |
Phase III | Synthesis and cloning of an scFv with selected CAR domains into a lentivirus vector. Generation of 1x108 lentivirus viral particles. | $6,000 |
Phase IV | Lentiviral transduction, FACS analysis to validate CAR expression in NK cells. | $5,000 |
Phase V | Measurements of CAR expression, cytokines (such as IFN-γ, IL-2, GranzymeB) and cytotoxicity via RTCA. | $6,000 |
PLAN B
DEVELOPMENT STAGE | DESCRIPTION | PRICE |
---|---|---|
Phase III | Synthesis and cloning of an scFv with selected CAR domains into a lentivirus vector. Generation of 1x108 lentivirus viral particles. | $6,000 |
Phase IV | Lentiviral transduction, FACS analysis to validate CAR expression in NK cells. | $5,000 |
Phase VI | NSG/NOG xenograft model | starting at $15,000 |
We also have off the shelf solutions that will quickly establish and advance your projects in the following areas: