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KIT Primary Antibody
|Aliases||PBT; SCFR; C-Kit; CD117; KIT|
|Formulation||The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Liquid in PBS containing 50% glycerol and 0.03% sodium azide.|
|Immunogen||Synthesized peptide derived from internal of human KIT.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|Species Reactivity||Human, Mouse|
|IHC_P (Immunohistochemistry)||1/200 - 1/1000|
Figure 1: Western blot analysis using KIT Rabbit pAb against SW620 (1) and HCT116 (2) cell lysate.
Figure 2: Immunohistochemical analysis of paraffin-embedded epiploon tissues (left), belly tissues (right) using KIT Rabbit pAb with DAB staining.
|Description||his gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.|
|References (references)||1. Zhonghua Wai Ke Za Zhi. 2009 Jun 1;47(11):857-62.
2. Blood. 2010 Mar 25;115(12):2372-9.