VAMP2
The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG.
Cell Mol Immunol. 2018 Apr;15(4):353-366.
![Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/32440ea.jpg?v=1669029828)
![Figure 2:Flow cytometric analysis of Hela cells using VAMP2 mouse mAb (green) and negative control (red).](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/32440fcm-1.jpg?v=1669029828)
![Figure 3:Flow cytometric analysis of COS-7 cells using VAMP2 mouse mAb (green) and negative control (red).](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/32440fcm-2.jpg?v=1669029828)
![Figure 4:Immunohistochemical analysis of paraffin-embedded Medulla oblongata tissues using VAMP2 mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/32440ihc-1.jpg?v=1669029828)
![Figure 5:Immunohistochemical analysis of paraffin-embedded Brain tissues using VAMP2 mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/32440ihc-2.jpg?v=1669029828)
![Figure 6:Immunohistochemical analysis of paraffin-embedded Mouse cerebellum tissues using VAMP2 mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/32440ihc-3.jpg?v=1669029828)
![Figure 7:Immunohistochemical analysis of paraffin-embedded Rat brain tissues using VAMP2 mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/32440ihc-4.jpg?v=1669029828)
![Figure 8:Immunohistochemical analysis of paraffin-embedded Rabbit brain tissues using VAMP2 mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/32440ihc-5.jpg?v=1669029829)