USP11
Item Information
Catalog #
Size
Price
Description
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23
Product Overview
Entrez GenelD
8237
Aliases
UHX1
Clone#
2D7A11
Host / Isotype
Mouse / Mouse IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human USP11 expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4℃; -20℃ for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
References
1.Cancer Res. 2020 Nov 15;80(22):5076-5088.
2.J Biol Chem. 2019 Jan 11;294(2):424-436.
2.J Biol Chem. 2019 Jan 11;294(2):424-436.
Product Image
Western Blot
Figure 1:Western blot analysis using USP11 mouse mAb against Hela (1), LNcap (2), HepG2 (3), K562 (4), A549 (5) and Jurkat (6) cell lysate.
Immunofluorescence analysis
Figure 2:Flow cytometric analysis of Jurkat cells using USP11 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.