ULBP1 Primary Antibody

Item Information
Catalog # Size/Concentration Price
31744 100ug $341.00
Specification
AliasesN2DL-1; RAET1I; NKG2DL1
Clone#3A6F11
Entrez GeneID80329
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeMouse IgG1
ImmunogenPurified recombinant fragment of human ULBP1 (AA: 26-216) expressed in E. Coli.
MW28kDa
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
26-216
Catalog
31744
$341.00
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Images

Elisa

Cell Culture Products

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Cell Culture Products

Figure 2:Western blot analysis using ULBP1 mAb against human ULBP1 (AA: 26-216) recombinant protein. (Expected MW is 48.3 kDa)

Western Blot

Cell Culture Products

Figure 3:Western blot analysis using ULBP1 mAb against HEK293 (1) and ULBP1 (AA: 26-216)-hIgGFc transfected HEK293 (2) cell lysate.

Flow cytometric

Cell Culture Products

Figure 4:Flow cytometric analysis of Hela cells using ULBP1 mouse mAb (green) and negative control (red).

Product Overview
Description

The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

References (references)
References (references) 1.Oncotarget. 2016 Mar 29;7(13):15369-81. 2.Elife. 2015 Nov 13;4. pii: e08474.

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