UBE2C Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesUBCH10; dJ447F3.2
ProductOrderU
Clone#1F5D3
Entrez GenelD11065
FormulationPurified antibody in PBS with 0.05% sodium azide.
HostMouse
IsotypeIgG2a
ImmunogenPurified recombinant fragment of human UBE2C (AA: FULL(1-179)) expressed in E. Coli.
MW19.7kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
FULL(1-179)
Catalog#: 30693
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Images
Western Blot
Figure 1: Western blot analysis using UBE2C mAb against human UBE2C (AA: FULL(1-179)) recombinant protein. (Expected MW is 45.6 kDa)
Figure 1: Western blot analysis using UBE2C mAb against human UBE2C (AA: FULL(1-179)) recombinant protein. (Expected MW is 45.6 kDa)
Western Blot
Figure 2: Western blot analysis using UBE2C mAb against HEK293 (1) and UBE2C (AA: FULL(1-179))-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using UBE2C mAb against HEK293 (1) and UBE2C (AA: FULL(1-179))-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using UBE2C mouse mAb with DAB staining.
Figure 3: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using UBE2C mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 4: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using UBE2C mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using UBE2C mouse mAb with DAB staining.
Western Blot
Figure 6:Western blot analysis using UBE2C mouse mAb against Hela (1), and Raji (2) cell lysate.
Figure 6:Western blot analysis using UBE2C mouse mAb against Hela (1), and Raji (2) cell lysate.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.

References (references)
References (references)1. J Cancer Res Clin Oncol. 2012 Nov;138(11):1951-61.
2. Histopathology. 2009 May;54(6):731-40.