Tyro3 Primary Antibody

Item Information

Catalog #

Size

Price

Description

Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.

Product Overview

Entrez GenelD

7301

Aliases

BYK; Brt; Dtk; RSE; Sky; Tif; FLJ16467

Clone#

7A10C11; 7A10G4

Species Reactivity

Human

Immunogen

Purified recombinant fragment of Tyro3 expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

4°C; -20°C for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

ELISA

1/10000

References

1. Christoph Heiring, Bjon Dahlbok, and Yves A. Muller. J. Biol. Chem Feb 2004; 279: 6952 - 6958.
2. Sassan Hafizi, Anna Gustafsson, Jonas Stenhoff. Int J Biochem Cell Biol. 2005 Nov;37(11):2344-56.

Product Image

Western Blot