Tyro3 Primary Antibody
Item Information
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Description
Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.
Product Overview
Entrez GenelD
7301
Aliases
BYK; Brt; Dtk; RSE; Sky; Tif; FLJ16467
Clone#
7A10C11; 7A10G4
Species Reactivity
Human
Immunogen
Purified recombinant fragment of Tyro3 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Christoph Heiring, Bjon Dahlbok, and Yves A. Muller. J. Biol. Chem Feb 2004; 279: 6952 - 6958.
2. Sassan Hafizi, Anna Gustafsson, Jonas Stenhoff. Int J Biochem Cell Biol. 2005 Nov;37(11):2344-56.
2. Sassan Hafizi, Anna Gustafsson, Jonas Stenhoff. Int J Biochem Cell Biol. 2005 Nov;37(11):2344-56.
Product Image
Western Blot
Figure 1: Western blot analysis using TYRO3 mouse mAb against truncated TYRO3 recombinant protein (1) and HepG2 cell lysate (2).
For Research Use Only. Not for use in diagnostic procedures.