TNFRSF11A Primary Antibody

Item Information

Catalog #

Size

Price

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

Product Overview

Entrez GenelD

8792

Aliases

FEO; OFE; ODFR; OSTS; PDB2; RANK; CD265; OPTB7; TRANCER; LOH18CR1; TRANCE-R

Clone#

3A9G2

Host / Isotype

Mouse / Mouse IgG1

Species Reactivity

Human, Mouse, Rat

Immunogen

Purified recombinant fragment of human TNFRSF11A (AA: extra 30-212) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Product Applications

WB (Western Blot)

1/500 - 1/2000

FCM (Flow Cytometry)

1/200 - 1/400

ELISA

1/10000

References

1.Orthod Craniofac Res. 2020 May;23(2):210-222.
2.J Bone Miner Res. 2019 Oct;34(10):1873-1879.

Product Image

Elisa

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Figure 2:Western blot analysis using TNFRSF11A mAb against human TNFRSF11A (AA: extra 30-212) recombinant protein. (Expected MW is 46 kDa)

Western Blot

Figure 3:Western blot analysis using TNFRSF11A mAb against HEK293-6e (1) and TNFRSF11A (AA: extra 30-212)-hIgGFc transfected HEK293-6e (2) cell lysate.

Western Blot