TLR2 Primary Antibody
Item Information
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Price
Description
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
Product Overview
Entrez GenelD
7097
Aliases
TIL4; CD282; TLR2
Clone#
2D6
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human TLR2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Ginekol Pol. 2009 Dec;80(12):914-9. Polish.
2. BMC Med Genet. 2010 Mar 2;11:37.
2. BMC Med Genet. 2010 Mar 2;11:37.
Product Image
Western Blot
Figure 1: Western blot analysis using TLR2 mouse mAb against Hela (1) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.