TLR2 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesTIL4; CD282; TLR2
ProductOrderT
Clone#2D6
Entrez GenelD7097
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human TLR2 expressed in E. Coli.
MW100kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
N
Catalog#: 20424
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Images
Western Blot
Figure 1: Western blot analysis using TLR2 mouse mAb against Hela (1) cell lysate.
Figure 1: Western blot analysis using TLR2 mouse mAb against Hela (1) cell lysate.
Product Overview
Description

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

References (references)
References (references)1. Ginekol Pol. 2009 Dec;80(12):914-9. Polish.
2. BMC Med Genet. 2010 Mar 2;11:37.