TGFb1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesCED; LAP; DPD1; TGFB; TGFbeta
ProductOrderT
Clone#7F6
Entrez GenelD7040
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human TGFb1 (AA: 62-195) expressed in E. Coli.

MW44.3kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
62-195
Catalog#: 30383
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Images
Western Blot
Figure 1: Western blot analysis using TGFb1 mAb against human TGFb1 recombinant protein. (Expected MW is 41 kDa)
Figure 1: Western blot analysis using TGFb1 mAb against human TGFb1 recombinant protein. (Expected MW is 41 kDa)
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded lung cancer tissues using TGFb1 mouse mAb with DAB staining.
Figure 2: Immunohistochemical analysis of paraffin-embedded lung cancer tissues using TGFb1 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded lymphoid tissue tissues using TGFb1 mouse mAb with DAB staining.
Figure 3: Immunohistochemical analysis of paraffin-embedded lymphoid tissue tissues using TGFb1 mouse mAb with DAB staining.
Flow cytometric
Figure 4: Flow cytometric analysis of A549 cells using TGFb1 mouse mAb (green) and negative control (red).
Figure 4: Flow cytometric analysis of A549 cells using TGFb1 mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease

References (references)
References (references)1.Cell. 2011 Oct 28;147(3):565-76.
2.Kobe J Med Sci. 2011 May 11;56(6):E242-52.