TERF2 Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
Product Overview
Entrez GenelD
7014
Aliases
TRF2; TRBF2
Clone#
3H6B4
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human TERF2 (AA: 324-500) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. PLoS One. 2012;7(4):e34386.
2. Breast Cancer Res Treat. 2011 Jun;127(3):623-30.
2. Breast Cancer Res Treat. 2011 Jun;127(3):623-30.
Product Image
Western Blot
Figure 1: Western blot analysis using TERF2 mAb against human TERF2 (AA: 324-500) recombinant protein. (Expected MW is 39.7 kDa)
Western Blot
Figure 2: Western blot analysis using TERF2 mAb against HEK293 (1) and TERF2 (AA: 324-500)-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using TERF2 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 4: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using TERF2 mouse mAb with DAB staining.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.