Mouse Monoclonal Antibody to TDP43

Item Information
Catalog # Size/Concentration Price
90009 1.0mg/ml $358.00
Specification
AliasesALS10; TDP-43
Clone#6G2D8
Entrez GeneID23435
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human TDP43 (AA: free peptide) expressed in E. Coli.
MW44.7kDa
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
IHC_P (Immunohistochemistry) 1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
Free peptide
Catalog
90009

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Images

Elisa

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Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

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Figure 2:Western blot analysis using TDP43 mouse mAb against Hela (1), HEK293 (2), MCF-7 (3), and A549 (4) cell lysate.

Flow cytometric analysis

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Figure 3:Flow cytometric analysis of A431 cells using TDP43 mouse mAb (green) and negative control (red).

Flow cytometric analysis

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Figure 4:Flow cytometric analysis of Hela cells using TDP43 mouse mAb (green) and negative control (red).

Flow cytometric analysis

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Figure 5:Flow cytometric analysis of HepG2 cells using TDP43 mouse mAb (green) and negative control (red).

Immunohistochemical analysis

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Figure 6:Immunohistochemical analysis of paraffin-embedded baldder cancer tissues using TDP43 mouse mAb with DAB staining.

Immunohistochemical analysis

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Figure 7:Immunohistochemical analysis of paraffin-embedded liver cancer tissues using TDP43 mouse mAb with DAB staining.

Immunohistochemical analysis

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Figure 8:Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using TDP43 mouse mAb with DAB staining.

Immunofluorescence analysis

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Figure 9:Immunofluorescence analysis of Hela cells using TDP43 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Product Overview
Description

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]

References (references)
References (references) 1,Adv Exp Med Biol. 2021;1281:201-217.2,Science. 2021 Feb 5;371(6529):eabb4309.

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