SV2C

Item Information

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Price

Description

SV2C (Synaptic Vesicle Glycoprotein 2C) is a Protein Coding gene. Diseases associated with SV2C include Foodborne Botulism and Alcohol-Related Birth Defect. Among its related pathways are Toxicity of botulinum toxin type F (BoNT/F) and Uptake and actions of bacterial toxins. Gene Ontology (GO) annotations related to this gene include transporter activity and transmembrane transporter activity. An important paralog of this gene is SV2A.

Product Overview

Entrez GenelD

22987

Clone#

5G11D10

Host / Isotype

Mouse / Mouse IgG1

Species Reactivity

Human

Immunogen

Purified recombinant fragment of human SV2C (AA: extra mix) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

4℃; -20℃ for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

IHC_P(Immunohistochemistry)

1/200 - 1/1000

ICC (Immunocytochemistry)

1/200 - 1/1000

FCM (Flow Cytometry)

1/200 - 1/400

ELISA

1/10000

References

1,Nat Struct Mol Biol . 2016 Jul;23(7):656-62.
2,Trends Biochem Sci . 2014 Nov;39(11):517-26.

Product Image

Elisa

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Figure 2:Western blot analysis using SV2C mAb against human SV2C (AA: extra mix) recombinant protein. (Expected MW is 22.7 kDa)

Western Blot

Figure 3:Western blot analysis using SV2C mAb against HEK293-6e (1) and SV2C (AA: extra mix)-hIgGFc transfected HEK2936e (2) cell lysate.

Immunohistochemical analysis

Figure 4:Immunofluorescence analysis of Hela cells using SV2C mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Immunofluorescence analysis