Survivin Primary Antibody
Baculoviral IAP repeat-containing 5 (survivin). This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Ascitic fluid containing 0.03% sodium azide.
4°C; -20°C for long term storage
Figure 1: Western blot analysis using survivin mouse mAb against full-length survivin recombinant protein (1) and full-length survivin-GFP transfected Cos7 cell lysate (2).
Figure 2: Western blot analysis using Survivin mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY Survivin cDNA (2).
For Research Use Only. Not for use in diagnostic procedures.