SPP1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesOPN; BNSP; BSPI; ETA-1
ProductOrderS
Clone#7C5H12
Entrez GenelD6696
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human SPP1 (AA: 167-314) expressed in E. Coli.
MW35.4kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
167-314
Catalog#: 30443
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Images
Western Blot
Figure 1: Western blot analysis using SPP1 mAb against human SPP1 recombinant protein. (Expected MW is 42.6 kDa)
Figure 1: Western blot analysis using SPP1 mAb against human SPP1 recombinant protein. (Expected MW is 42.6 kDa)
Western Blot
Figure 2: Western blot analysis using SPP1 mAb against HEK293 (1) and SPP1 (AA: 167-314)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using SPP1 mAb against HEK293 (1) and SPP1 (AA: 167-314)-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using SPP1 mouse mAb with DAB staining.
Figure 3: Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using SPP1 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 4: Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using SPP1 mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using SPP1 mouse mAb with DAB staining.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
DescriptionThe protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.


References (references)
References (references)1.Blood. 2012 May 31;119(22):5215-20.
2.J Cancer Res Ther. 2011 Apr-Jun;7(2):138-42.