SOX2 Primary Antibody
Item Information
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Size
Price
Description
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Product Overview
Entrez GenelD
6657
Aliases
ANOP3; MCOPS3
Clone#
10F10
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human SOX2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ICC (Immunocytochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18396-401.
2. J Biol Chem. 2008 Nov 28;283(48):33730-5.
3. Nature. 2008 Oct 23;455(7216):1124-8.
2. J Biol Chem. 2008 Nov 28;283(48):33730-5.
3. Nature. 2008 Oct 23;455(7216):1124-8.
Product Image
Western Blot
Figure 1: Western blot analysis using SOX2 mAb against HEK293 (1) and SOX2(AA: 2-317)-hIgGFc transfected HEK293 (2) cell lysate.
Immunofluorescence analysis
Figure 2: Immunofluorescence analysis of NTERA-2 cells using SOX2 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded lung cancer tissues (left) and esophageal cancer tissues (right) using SOX2 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.