SMN1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesSMA; SMN; SMA1; SMA2; SMA3; SMA4; SMA@; SMN2; SMNT; BCD541; T-BCD541
ProductOrderS
Clone#2F1
Entrez GenelD6606
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human SMN1 expressed in E. Coli.
MW39kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Monkey
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
148-294
Catalog#: 30220
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Images
Western Blot
Figure 1: Western blot analysis using SMN1 mouse mAb against HepG2 (1), Hela (2), K562 (3), Jurkat (4), SKBR-3 (5), A431 (6) and Cos7 (7) cell lysate.
Figure 1: Western blot analysis using SMN1 mouse mAb against HepG2 (1), Hela (2), K562 (3), Jurkat (4), SKBR-3 (5), A431 (6) and Cos7 (7) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded testis tissues (left) and lung cancer tissues (right) using SMN1 mouse mAb with DAB staining.
Figure 2: Immunohistochemical analysis of paraffin-embedded testis tissues (left) and lung cancer tissues (right) using SMN1 mouse mAb with DAB staining.
Flow cytometric
Figure 3: Flow cytometric analysis of HepG2 cells using SMN1 mouse mAb (green) and negative control (purple).
Figure 3: Flow cytometric analysis of HepG2 cells using SMN1 mouse mAb (green) and negative control (purple).
Elisa
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Product Overview
Description

This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein.

References (references)
References (references)1. J Med Genet. 2009 Sep;46(9):641-4.
2. RNA. 2009 Apr;15(4):515-23.
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