SERPINE1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesPAI; PAI1; PAI-1; PLANH1
ProductOrderS
Clone#1D5
Entrez GenelD5054
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human SERPINE1 expressed in E. Coli.
MW45kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
194-316
Catalog#: 30306
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Images
Western Blot
Figure 1: Western blot analysis using SERPINE1 mAb against human SERPINE1 (AA: 194-316) recombinant protein. (Expected MW is 45kDa kDa)
Figure 1: Western blot analysis using SERPINE1 mAb against human SERPINE1 (AA: 194-316) recombinant protein. (Expected MW is 45kDa kDa)
Western Blot
Figure 2: Western blot analysis using SERPINE1 mAb against HEK293 (1) and SERPINE1 (AA: 194-316)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using SERPINE1 mAb against HEK293 (1) and SERPINE1 (AA: 194-316)-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded lung cancer tissues using SERPINE1 mouse mAb with DAB staining.
Figure 3: Immunohistochemical analysis of paraffin-embedded lung cancer tissues using SERPINE1 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 4: Immunohistochemical analysis of paraffin-embedded kidney cancer tissues using SERPINE1 mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded kidney cancer tissues using SERPINE1 mouse mAb with DAB staining.
Flow cytometric
Figure 5: Flow cytometric analysis of NIH/3T3 cells using SERPINE1 mouse mAb (green) and negative control (red).
Figure 5: Flow cytometric analysis of NIH/3T3 cells using SERPINE1 mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References (references)
References (references)1. Biol Pharm Bull. 2009 Apr;32(4):573-7.
2. Clin Chim Acta. 2009 Apr;402(1-2):189-92.