SERPINA Primary Antibody

Item Information
Catalog # Size/Concentration Price
32009 100ug $341.00
Specification
AliasesPI; A1A; AAT; PI1; A1AT; nNIF; PRO2275; alpha1AT
Clone#7D3A2
Entrez GeneID5265
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeMouse IgG1
ImmunogenPurified recombinant fragment of human SERPINA (AA: 269-419) expressed in E. Coli.
MW19.3/46.7/53 kDa(abcam,santa)
Application
ELISA1/10000
IHC_P (Immunohistochemistry) 1/200-1/1000
FCM (Flow Cytometry)1/200-1/400
WB (Western Blot)1/500 - 1/2000
Sequence
AA: 269-419
Catalog
32009
$341.00
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Images

ELISA

Cell Culture Products
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)

WESTERN BLOT

Cell Culture Products
Figure 2: Western blot analysis using SERPINA mAb against human SERPINA (AA: 269-419) recombinant protein. (Expected MW is 35.7 kDa)

WESTERN BLOT

Cell Culture Products
Figure 3: Western blot analysis using SERPINA mAb against HEK293-6e (1) and SERPINA (AA: 269-419)-hIgGFc transfected HEK293-6e (2) cell lysate.

FLOW CYTOMETRY

Cell Culture Products
Figure 4: Flow cytometric analysis of Hela cells using SERPINA mouse mAb (green) and negative control (red).

FLOW CYTOMETRY

Cell Culture Products
Figure 5: Flow cytometric analysis of Jurkat cells using SERPINA mouse mAb (green) and negative control (red).

IMMUNOHISTOCHEMISTRY

Cell Culture Products
Figure 6: Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using SERPINA mouse mAb with DAB staining.

IMMUNOHISTOCHEMISTRY

Cell Culture Products
Figure 7: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using SERPINA mouse mAb with DAB staining.
Product Overview
Description

The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2020]

References (references)
References (references) 1,Rev Med Virol. 2020 Aug 26;e2157.2,Clin Liver Dis. 2020 Aug;24(3):483-492.

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