SCGB2A2 Primary Antibody

Item Information

Catalog #

Size

Price

Description

Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.Tissue specificity: Mammary gland specific. Over-expressed in breast cancer.

Product Overview

Entrez GenelD

4250

Aliases

MGB1; UGB2; MGC71974; SCGB2A2

Clone#

3C8

Host / Isotype

Mouse / IgG1

Species Reactivity

Human

Immunogen

Purified recombinant fragment of human SCGB2A2 expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

4°C; -20°C for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

IHC_P(Immunohistochemistry)

1/200 - 1/1000

ICC (Immunocytochemistry)

1/200 - 1/1000

FCM (Flow Cytometry)

1/200 - 1/400

ELISA

1/10000

References

1. Ann Oncol. 2006 Jun;17 Suppl 7:vii41-5.
2. Mod Pathol. 2007 Feb;20(2):208-14.

Product Image

Western Blot

Figure 1: Western blot analysis using SCGB2A2 mAb against human SCGB2A2 (AA: 2-93) recombinant protein. (Expected MW is 35.8 kDa)

Immunohistochemical analysis

Figure 2: Immunohistochemical analysis of paraffin-embedded mammary cancer tissues using SCGB2A2 mouse mAb with DAB staining.

Immunofluorescence analysis

Figure 3: Immunofluorescence analysis of Hela cells using SCGB2A2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Flow cytometric