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SCGB2A2 Primary Antibody
|Aliases||MGB1; UGB2; MGC71974; SCGB2A2|
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Immunogen||Purified recombinant fragment of human SCGB2A2 expressed in E. Coli.\
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|ICC (Immunocytochemistry)||1/200 - 1/1000|
|IHC_P (Immunohistochemistry)||1/200 - 1/1000|
|FCM (Flow Cytometry)||1/200 - 1/400|
Figure 1: Western blot analysis using SCGB2A2 mAb against human SCGB2A2 (AA: 2-93) recombinant protein. (Expected MW is 35.8 kDa)
Figure 2: Immunohistochemical analysis of paraffin-embedded mammary cancer tissues using SCGB2A2 mouse mAb with DAB staining.
Figure 3: Immunofluorescence analysis of Hela cells using SCGB2A2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Figure 4: Flow cytometric analysis of SK-BR-3 cells using SCGB2A2 mouse mAb (green) and negative control (purple).
|Description||Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.Tissue specificity: Mammary gland specific. Over-expressed in breast cancer.|
|References (references)||1. Ann Oncol. 2006 Jun;17 Suppl 7:vii41-5.
2. Mod Pathol. 2007 Feb;20(2):208-14.