RUNX1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesAML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1; RUNX1
ProductOrderR
Clone#5A1
Entrez GenelD861
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenSynthesized peptide of human RUNX1.
MW55kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
434-447:NSPTNMAPSARLEE-C
Catalog#: 30171
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Images
Western Blot
Figure 1: Western blot analysis using RUNX1 mouse mAb against Jurkat cell lysate.
Figure 1: Western blot analysis using RUNX1 mouse mAb against Jurkat cell lysate.
Immunofluorescence analysis
Figure 2: Immunofluorescence analysis of Hela cells using RUNX1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Figure 2: Immunofluorescence analysis of Hela cells using RUNX1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Elisa
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Product Overview
Description

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.

References (references)
References (references)1. J Cell Physiol. 2009 Feb;218(2):343-9.
2. J Radiat Res (Tokyo). 2008 Sep;49(5):549-55.