RUNX1 Primary Antibody

Item Information

Catalog #

Size

Price

Description

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.

Product Overview

Entrez GenelD

861

Aliases

AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1; RUNX1

Clone#

5A1

Host / Isotype

Mouse / IgG1

Species Reactivity

Human

Immunogen

Synthesized peptide of human RUNX1.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

4°C; -20°C for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

ICC (Immunocytochemistry)

1/200 - 1/1000

ELISA

1/10000

References

1. J Cell Physiol. 2009 Feb;218(2):343-9.
2. J Radiat Res (Tokyo). 2008 Sep;49(5):549-55.

Product Image

Western Blot

Figure 1: Western blot analysis using RUNX1 mouse mAb against Jurkat cell lysate.

Immunofluorescence analysis

Figure 2: Immunofluorescence analysis of Hela cells using RUNX1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

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