PROM1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesRP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061
ProductOrderP
Clone#2F8C5
Entrez GenelD8842
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human PROM1 (AA: 20-108) expressed in E. Coli.
MW97.2kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
Extra(20-108)
Catalog#: 30841
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Images
Elisa
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western Blot
Figure 2:Western blot analysis using PROM1 mAb against human PROM1 (AA: 20-108) recombinant protein. (Expected MW is 36.1 kDa)
Figure 2:Western blot analysis using PROM1 mAb against human PROM1 (AA: 20-108) recombinant protein. (Expected MW is 36.1 kDa)
Western Blot
Figure 3:Western blot analysis using PROM1 mAb against HEK293 (1) and PROM1 (AA: 20-108)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3:Western blot analysis using PROM1 mAb against HEK293 (1) and PROM1 (AA: 20-108)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of Hela cells using PROM1 mouse mAb (green) and negative control (red).
Figure 4:Flow cytometric analysis of Hela cells using PROM1 mouse mAb (green) and negative control (red).
Product Overview
DescriptionThis gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
References (references)
References (references)1.Gastric Cancer. 2014 Jan;17(1):97-106.
2.Cancer Biomark. 2012;12(2):97-105.