PRDM1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesBLIMP1; PRDI-BF1; MGC118922; MGC118923; MGC118924; MGC118925; PRDM1
ProductOrderP
Clone#5E7
Entrez GenelD639
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human PRDM1 expressed in E. Coli.
MW88kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Mouse
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
188-375
Catalog#: 30020
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Images
Western Blot
Figure 1: Western blot analysis using PRDM1 mouse mAb against Raji (1, 2), L1210 (3) and TPH-1 (4) cell lysate.
Figure 1: Western blot analysis using PRDM1 mouse mAb against Raji (1, 2), L1210 (3) and TPH-1 (4) cell lysate.
Product Overview
Description

PRDM1/Blimp1 is a repressor of beta-interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. The transcription of this gene is increased upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

References (references)
References (references)1. Nat Cell Biol. 2006 Jun;8(6):623-30.
2. Int J Hematol. 2007 Dec;86(5):429-37.
3. Nat Genet. 2008 Aug;40(8):955-62.