PPY Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesPNP
ProductOrderP
Clone#2G5D12
Entrez GenelD5539
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human PPY (AA: 1-95) expressed in E. Coli.
MW10.4kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
full(1-95)
Catalog#: 30433
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Images
Western Blot
Figure 1: Western blot analysis using PPY mAb against human PPY recombinant protein. (Expected MW is 35.9 kDa)
Figure 1: Western blot analysis using PPY mAb against human PPY recombinant protein. (Expected MW is 35.9 kDa)
Flow cytometric
Figure 2: Flow cytometric analysis of HepG2 cells using PPY mouse mAb (green) and negative control (purple).
Figure 2: Flow cytometric analysis of HepG2 cells using PPY mouse mAb (green) and negative control (purple).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
DescriptionThis gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.



References (references)
References (references)1.Am J Clin Nutr. 2011 Oct;94(4):967-72.
2.Pharm Res. 2012 Jun;29(6):1698-711.