PIK3CG Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesPI3K; PIK3; PI3CG; PI3Kgamma; p110gamma; p120-PI3K
ProductOrderP
Clone#4B5D2
Entrez GenelD5294
FormulationPurified antibody in PBS with 0.05% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human PIK3CG (AA: 1-100) expressed in E. Coli.
MW126.5kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
1-100
Catalog#: 30687
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Images
Western Blot
Figure 1: Western blot analysis using PIK3CG mAb against human PIK3CG (AA: 1-100) recombinant protein. (Expected MW is 37.5 kDa)
Figure 1: Western blot analysis using PIK3CG mAb against human PIK3CG (AA: 1-100) recombinant protein. (Expected MW is 37.5 kDa)
Western Blot
Figure 2: Western blot analysis using PIK3CG mAb against HEK293 (1) and PIK3CG (AA: 1-100)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using PIK3CG mAb against HEK293 (1) and PIK3CG (AA: 1-100)-hIgGFc transfected HEK293 (2) cell lysate.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.

References (references)
References (references)1. Lab Invest. 2013 May;93(5):566-76.
2. Biochem Biophys Res Commun. 2011 Jan 28;404(4):968-73.