PIK3CG Primary Antibody

Item Information
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Size
Price
Description

This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.

Product Overview
Entrez GenelD
5294
Aliases
PI3K; PIK3; PI3CG; PI3Kgamma; p110gamma; p120-PI3K
Clone#
4B5D2
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human PIK3CG (AA: 1-100) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Lab Invest. 2013 May;93(5):566-76.
2. Biochem Biophys Res Commun. 2011 Jan 28;404(4):968-73.
Product Image
Western Blot
Figure 1: Western blot analysis using PIK3CG mAb against human PIK3CG (AA: 1-100) recombinant protein. (Expected MW is 37.5 kDa)
Figure 1: Western blot analysis using PIK3CG mAb against human PIK3CG (AA: 1-100) recombinant protein. (Expected MW is 37.5 kDa)
Western Blot
Figure 2: Western blot analysis using PIK3CG mAb against HEK293 (1) and PIK3CG (AA: 1-100)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using PIK3CG mAb against HEK293 (1) and PIK3CG (AA: 1-100)-hIgGFc transfected HEK293 (2) cell lysate.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.