PGC-1alpha Primary Antibody

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Description

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. 

Product Overview
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
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Western Blot
Figure 1: Western blot analysis using PGC-1alpha mAb against human PGC-1alpha (AA: 570-798) recombinant protein. (Expected MW is 70 kDa)
Figure 1: Western blot analysis using PGC-1alpha mAb against human PGC-1alpha (AA: 570-798) recombinant protein. (Expected MW is 70 kDa)
Western Blot
Figure 2: Western blot analysis using PGC-1alpha mAb against HEK293 (1) and PGC-1alpha-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using PGC-1alpha mAb against HEK293 (1) and PGC-1alpha-hIgGFc transfected HEK293 (2) cell lysate.
Elisa
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
For Research Use Only. Not for use in diagnostic procedures.