PDXK

Item Information

Catalog #

Size

Price

Description

The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Product Overview

Entrez GenelD

8566

Aliases

PKH; PNK; HMSN6C; PRED79; C21orf97; HEL-S-1a; C21orf124

Clone#

4B4G3

Host / Isotype

Mouse / Mouse IgG1

Species Reactivity

Human, Mouse

Immunogen

Purified recombinant fragment of human PDXK (AA:1-312) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

4℃; -20℃ for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

IHC_P(Immunohistochemistry)

1/200 - 1/1000

ICC (Immunocytochemistry)

1/50 - 1/200

FCM (Flow Cytometry)

1/200 - 1/400

References

1.Ann Neurol. 2010 Mar;67(3):411-2; author reply 412.
2.Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2020 Jun;36(6):542-548.

Product Image

Western Blot

Figure 1:Western blot analysis using PDXK mouse mAb against Hela (1), HepG2 (2), MCF-7 (3), HEK293 (4), mouse liver (5) and mouse kidney (6) cell lysate.

Immunohistochemical analysis

Figure 2:Immunofluorescence analysis of Hala cells using PDXK mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Immunofluorescence analysis