PDE1B Primary Antibody
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Ascitic fluid containing 0.03% sodium azide.
4°C; -20°C for long term storage
Figure 1: Western blot analysis using PDE1B mAb against human PDE1B recombinant protein. (Expected MW is 44.4 kDa)
Figure 2: Western blot analysis using PDE1B mAb against HEK293 (1) and PDE1B (AA: 370-536)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3: Western blot analysis using PDE1B mouse mAb against A549 (1), SK-MES-1 (2), PC-12 (3), NIH3T3 (4), and 3T3-L1 (5) cell lysate.
Figure 4: Flow cytometric analysis of A549 cells using PDE1B mouse mAb (green) and negative control (red).
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.