PAX8 Primary Antibody

Item Information
Catalog # Size/Concentration Price
31986 100ug $358.00
Specification
Clone#1A1D3
Entrez GeneID7849
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeMouse IgG1
ImmunogenPurified recombinant fragment of human PAX8 (AA: 60-261) expressed in E. Coli.
MW48.2kDa
Application
ELISA1/10000
IHC_P (Immunohistochemistry) 1/200-1/1000
FCM (Flow Cytometry)1/200-1/400
WB (Western Blot)1/500 - 1/2000
Sequence
AA: 60-261
Catalog
31986
$358.00
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Images

ELISA

Cell Culture Products
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)

WESTERN BLOT

Cell Culture Products
Figure 2: Western blot analysis using PAX8 mAb against human PAX8 (AA: 60-261) recombinant protein. (Expected MW is 25 kDa)

WESTERN BLOT

Cell Culture Products
Figure 3: Western blot analysis using PAX8 mAb against HEK293-6e (1) and PAX8 (AA: 60-261)-hIgGFc transfected HEK293 (2) cell lysate.

WESTERN BLOT

Cell Culture Products
Figure 4: Western blot analysis using PAX8 mouse mAb against HL-60 (1), HEK293 (2), Raji (3), Hela (4), Jurkat (5), A431 (6), A549 (7), and K562 (8) cell lysate.

FLOW CYTOMETRY

Cell Culture Products
Figure 5: Flow cytometric analysis of SK-OV-3 cells using PAX8 mouse mAb (green) and negative control (red).

IMMUNOHISTOCHEMISTRY

Cell Culture Products
Figure 6: Immunohistochemical analysis of paraffin-embedded kidney tissues using PAX8 mouse mAb with DAB staining.

IMMUNOHISTOCHEMISTRY

Cell Culture Products
Figure 7: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using PAX8 mouse mAb with DAB staining.
Product Overview
Description

This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.

References (references)
References (references) 1.BMC Mol Cell Biol. 2019 Dec 27;20(1):61. 2.PLoS One. 2017 Mar 24;12(3):e0173700.

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