PARK7
Item Information
Catalog #
Size
Price
Description
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
Product Overview
Entrez GenelD
11315
Aliases
DJ1; DJ-1; GATD2; HEL-S-67p
Clone#
2B1G12
Host / Isotype
Mouse / Mouse IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human PARK7 (AA: 1-189) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4℃; -20℃ for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Biochemistry (Mosc). 2021 Jun;86(6):627-640.
2.Sci Rep. 2021 Jul 16;11(1):14582.
2.Sci Rep. 2021 Jul 16;11(1):14582.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using PARK7 mAb against human PARK7 (AA: 1-189) recombinant protein. (Expected MW is 45.8 kDa)
Western Blot
Figure 3:Western blot analysis using PARK7 mAb against HEK293-6e (1) and PARK7 (AA: 1-189)-hIgGFc transfected HEK293-6e (2) cell lysate.
Western Blot
Figure 4:Western blot analysis using PARK7 mouse mAb against A549 (1), A431 (2),K562 (3),Hela(4), SH-SY5Y (5) and SW480 (6) cell lysate.
Immunofluorescence analysis
Figure 5:Flow cytometric analysis of HepG2 cells using PARK7 mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 6:Immunohistochemical analysis of paraffin-embedded human brain tissues using PARK7 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 7:Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using PARK7 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.