The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
Purified antibody in PBS with 0.05% sodium azide
4℃; -20℃ for long term storage
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using PARK7 mAb against human PARK7 (AA: 1-189) recombinant protein. (Expected MW is 45.8 kDa)
Figure 3:Western blot analysis using PARK7 mAb against HEK293-6e (1) and PARK7 (AA: 1-189)-hIgGFc transfected HEK293-6e (2) cell lysate.
Figure 4:Western blot analysis using PARK7 mouse mAb against A549 (1), A431 (2),K562 (3),Hela(4), SH-SY5Y (5) and SW480 (6) cell lysate.
Figure 5:Flow cytometric analysis of HepG2 cells using PARK7 mouse mAb (green) and negative control (red).
Figure 6:Immunohistochemical analysis of paraffin-embedded human brain tissues using PARK7 mouse mAb with DAB staining.
Figure 7:Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using PARK7 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.