PAK3 Primary Antibody
The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified.
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using PAK3 mAb against human PAK3 (AA: 1-100) recombinant protein. (Expected MW is 37 kDa)
Figure 3:Western blot analysis using PAK3 mAb against HEK293 (1) and PAK3 (AA: 1-100)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Western blot analysis using PAK3 mouse mAb against Hela (1), SK-N-SH (2), T47D (3), COS7 (4), and HepG2 (5) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.