PAK3 Primary Antibody
Item Information
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Size
Price
Description
The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified.
Product Overview
Entrez GenelD
5063
Aliases
ARA; bPAK; MRX30; MRX47; OPHN3; PAK-3; PAK3beta; beta-PAK
Clone#
4G8F11
Host / Isotype
Mouse / IgG1
Species Reactivity
Human, Monkey
Immunogen
Purified recombinant fragment of human PAK3 (AA: 1-100) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1.J Mol Biol. 2014 Oct 23;426(21):3520-38.
2.J Biol Chem. 2011 Nov 18;286(46):40044-59.
2.J Biol Chem. 2011 Nov 18;286(46):40044-59.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using PAK3 mAb against human PAK3 (AA: 1-100) recombinant protein. (Expected MW is 37 kDa)
Western Blot
Figure 3:Western blot analysis using PAK3 mAb against HEK293 (1) and PAK3 (AA: 1-100)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 4:Western blot analysis using PAK3 mouse mAb against Hela (1), SK-N-SH (2), T47D (3), COS7 (4), and HepG2 (5) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.