P2RY1 Primary Antibody
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
Purified recombinant fragment of human P2RY1 (AA: extra mix) expressed in E. Coli.
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using P2RY1 mAb against human P2RY1 (AA: extra mix) recombinant protein. (Expected MW is 13 kDa)
Figure 3:Western blot analysis using P2RY1 mAb against HEK293 (1) and P2RY1 (AA: extra mix)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Western blot analysis using P2RY1 mouse mAb against SPC-A-1 (1) and C6 (2) cell lysate.
Figure 5:Flow cytometric analysis of Hela cells using P2RY1 mouse mAb (green) and negative control (red).
Figure 6:Flow cytometric analysis of K562 cells using P2RY1 mouse mAb (green) and negative control (red).
Figure 7:Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using P2RY1 mouse mAb with DAB staining.
Figure 8:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using P2RY1 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.