Oct4 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesOCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; MGC22487; POU5F1
ProductOrderO
Clone#5F7
Entrez GenelD5460
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenSynthesized peptide of human Oct4.
MW45kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
GVESNSDGASPEPC
Catalog#: 30147
Inquire
Contact us to order
Images
Western Blot
Figure 1: Western blot analysis using Oct4 mouse mAb against NTERA-2 cell lysate (1).
Figure 1: Western blot analysis using Oct4 mouse mAb against NTERA-2 cell lysate (1).
Product Overview
Description

This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. (provided by RefSeq).Tissue specificity: Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.

References (references)
References (references)1. J Biol Chem. 2008 Dec 19;283(51):35825-33.
2. Dev Genes Evol. 2008 Oct;218(10):561-6.
3. Stem Cells. 2008 Sep;26(9):2419-24.