NTRK3 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesTRKC; gp145(trkC)
ProductOrderN
Clone#4G5
Entrez GenelD4916
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant extracellular fragment of human NTRK3 (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.
MW94kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
Extra(32-429)74.1
Catalog#: 20383
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Images
Western Blot
Figure 1: Western blot analysis using NTRK3 mouse mAb against extracellular domain of human NTRK3 (aa32-429).
Figure 1: Western blot analysis using NTRK3 mouse mAb against extracellular domain of human NTRK3 (aa32-429).
Product Overview
Description

NTRK3 (neurotrophic tyrosine kinase, receptor, type 3), it is a member of the neurotrophic tyrosine receptor kinase (NTRK) family and plays an important role in the development and maintenance of neural tissues. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.

References (references)
References (references)1. BMC Cancer. 2007 Oct 31;7:202.
2. J Pathol. 2002 Aug;197(5):661-7.