?Np63? Primary Antibody

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Description

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8.

Product Overview
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
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ELISA
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
FLOW CYTOMETRY
Figure 2: Flow cytometric analysis of Hela cells using TP63 mouse mAb (green) and negative control (red).
Figure 2: Flow cytometric analysis of Hela cells using TP63 mouse mAb (green) and negative control (red).
IMMUNOHISTOCHEMISTRY
Figure 3: Immunohistochemical analysis of paraffin-embedded bladder Cancer tissues using TP63 mouse mAb with DAB staining.
Figure 3: Immunohistochemical analysis of paraffin-embedded bladder Cancer tissues using TP63 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.