NKX2.5 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesCSX; NKX2E
ProductOrderN
Clone#2E1
Entrez GenelD1482
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human NKX2.5 expressed in E. Coli.
MW35kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
aa20-180
Catalog#: 20388
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Images
Western Blot
Figure 1: Western blot analysis using NKX2.5 mouse mAb against full-length NKX2.5 (aa1-324)-hIgGFc transfected HEK293 cell lysate (1).
Figure 1: Western blot analysis using NKX2.5 mouse mAb against full-length NKX2.5 (aa1-324)-hIgGFc transfected HEK293 cell lysate (1).
Product Overview
Description

NKX2.5: NK2 transcription factor related, locus 5 (Drosophila), also known as CSX. It is a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

References (references)
References (references)1. Stem Cells Dev. 2005 Aug;14(4):425-39.
2. Cancer Res. 2003 Sep 1;63(17):5329-34.
3. Circ J. 2002 Jun;66(6):561-3.