NKX2.5 Primary Antibody
Item Information
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Description
NKX2.5: NK2 transcription factor related, locus 5 (Drosophila), also known as CSX. It is a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.
Product Overview
Entrez GenelD
1482
Aliases
CSX; NKX2E
Clone#
2E1
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human NKX2.5 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Stem Cells Dev. 2005 Aug;14(4):425-39.
2. Cancer Res. 2003 Sep 1;63(17):5329-34.
3. Circ J. 2002 Jun;66(6):561-3.
2. Cancer Res. 2003 Sep 1;63(17):5329-34.
3. Circ J. 2002 Jun;66(6):561-3.
Product Image
Western Blot
Figure 1: Western blot analysis using NKX2.5 mouse mAb against full-length NKX2.5 (aa1-324)-hIgGFc transfected HEK293 cell lysate (1).
For Research Use Only. Not for use in diagnostic procedures.