MTHFR Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesMTHFR
ProductOrderM
Clone#5D3
Entrez GenelD4524
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human MTHFR expressed in E. Coli.
MW75kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Rat
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
339-499
Catalog#: 30204
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Images
Western Blot
Figure 1: Western blot analysis using MTHFR mouse mAb against Rat Heart cell lysate.
Figure 1: Western blot analysis using MTHFR mouse mAb against Rat Heart cell lysate.
Western Blot
Figure 2: Western blot analysis using MTHFR mAb against HEK293 (1) and MTHFR(AA: 339-499)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using MTHFR mAb against HEK293 (1) and MTHFR(AA: 339-499)-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded lung cancer using MTHFR mouse mAb with DAB staining.
Figure 3: Immunohistochemical analysis of paraffin-embedded lung cancer using MTHFR mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 4: Immunohistochemical analysis of paraffin-embedded intima cancer tissues (left) and prostate tissues (right) using MTHFR mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded intima cancer tissues (left) and prostate tissues (right) using MTHFR mouse mAb with DAB staining.
Elisa
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Product Overview
Description

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

References (references)
References (references)1. Kardiol Pol. 2008 Dec;66(12):1269-77.
2. Arq Bras Endocrinol Metabol. 2008 Nov;52(8):1374-81.