MSN Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
Aliasesmoesin
ProductOrderM
Clone#2C12
Entrez GenelD4478
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human MSN expressed in E. Coli.
MW67.8kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Monkey
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
292-491
Catalog#: 30338
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Images
Western Blot
Figure 1: Western blot analysis using MSN mAb against human MSN (AA: 292-491) recombinant protein. (Expected MW is 49.2 kDa)
Figure 1: Western blot analysis using MSN mAb against human MSN (AA: 292-491) recombinant protein. (Expected MW is 49.2 kDa)
Western Blot
Figure 2: Western blot analysis using MSN mouse mAb against HeLa (1), A431 (2),Jurkat(3), HEK293(4), and COS7 (5) cell lysate.
Figure 2: Western blot analysis using MSN mouse mAb against HeLa (1), A431 (2),Jurkat(3), HEK293(4), and COS7 (5) cell lysate.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded colon tissues using MSN mouse mAb with DAB staining.
Figure 3: Immunohistochemical analysis of paraffin-embedded colon tissues using MSN mouse mAb with DAB staining.
Flow cytometric
Figure 4: Flow cytometric analysis of Jurkat cells using MSN mouse mAb (green) and negative control (red).
Figure 4: Flow cytometric analysis of Jurkat cells using MSN mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.

References (references)
References (references)Int J Cancer. 2009 Apr 1;124(7):1614-21.
J Biol Chem. 2009 Jan 23;284(4):2419-34.