MRE11
Item Information
Catalog #
Size
Price
Description
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Product Overview
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4℃; -20℃ for long term storage
Product Image
Elisa

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot

Figure 2:Western blot analysis using MRE11 mouse mAb against Hela (1), A431 (2), MCF-7 (3), Jurkat (4), HepG2 (5), K562 (6), COS-7 (7), PC-12 (8) and NIH/3T3 (9) cell lysate.
Immunofluorescence analysis

Figure 3:Flow cytometric analysis of Hela cells using MRE11 mouse mAb (green) and negative control (red).
Immunofluorescence analysis

Figure 4:Flow cytometric analysis of K562 cells using MRE11 mouse mAb (green) and negative control (red).
Immunohistochemical analysis

Figure 5:Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using MRE11 mouse mAb with DAB staining.
Immunohistochemical analysis

Figure 6:Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using MRE11 mouse mAb with DAB staining.
Immunohistochemical analysis

Figure 7:Immunohistochemical analysis of paraffin-embedded Mouse testis tissues using MRE11 mouse mAb with DAB staining.
Immunohistochemical analysis

Figure 8:Immunohistochemical analysis of paraffin-embedded Rat testis tissues using MRE11 mouse mAb with DAB staining.
Immunohistochemical analysis

Figure 9:Immunohistochemical analysis of paraffin-embedded Rabbit testis tissues using MRE11 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.