MLXIPL Primary Antibody

Item Information

Catalog #

Size

Price

Description

This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.

Product Overview

Entrez GenelD

51085

Aliases

MIO; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14

Clone#

5D12D1

Host / Isotype

Mouse / IgG1

Species Reactivity

Human

Immunogen

Purified recombinant fragment of human MLXIPL (AA: 18-143) expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Product Applications

WB (Western Blot)

1/500 - 1/2000

ICC (Immunocytochemistry)

1/200 - 1/1000

ELISA

1/10000

References

1. Diabetes. 2012 Mar;61(3):574-85.
2. Biochim Biophys Acta. 2011 Dec;1811(12):1194-200.

Product Image

Western Blot

Figure 1: Western blot analysis using MLXIPL mAb against human MLXIPL recombinant protein. (Expected MW is 41 kDa)

Western Blot

Figure 2: Western blot analysis using MLXIPL mAb against HEK293 (1) and MLXIPL (AA: 18-143)-hIgGFc transfected HEK293 (2) cell lysate.

Immunofluorescence analysis

Figure 3: Immunofluorescence analysis of Hela cells using MLXIPL mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Elisa