MEF2A Primary Antibody
|Aliases||mef2; ADCAD1; RSRFC4; RSRFC9|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of human MEF2A (AA: 391-497) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|ICC (Immunocytochemistry)||1/200 - 1/1000|
|FCM (Flow Cytometry)||1/200 - 1/400|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using MEF2A mAb against human MEF2A (AA: 391-497) recombinant protein. (Expected MW is 38 kDa)
Figure 2: Western blot analysis using MEF2A mAb against HEK293 (1) and MEF2A (AA: 391-497)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3: Immunofluorescence analysis of Hela cells using MEF2A mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Secondary antibody from Fisher (Cat#: 35503)
Figure 4: Flow cytometric analysis of HepG2 cells using MEF2A mouse mAb (green) and negative control (red).
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
|Description||The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene. |
|References (references)||1. Cell Biochem Funct. 2012 Mar;30(2):108-13. |
2. Circ Cardiovasc Genet. 2009 Apr;2(2):165-72.