MAPK9 Primary Antibody

Item Information
Catalog # Size/Concentration Price
31737 100ug $341.00
Specification
AliasesJNK2; SAPK; p54a; JNK2A; JNK2B; PRKM9; JNK-55; SAPK1a; JNK2BETA; p54aSAPK; JNK2ALPHA
Clone#2F6H11
Entrez GeneID5601
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenMouse IgG1
MW39.1kDa
Application
ELISA1/10000
IHC_P (Immunohistochemistry) Purified recombinant fragment of human DFFB (AA: 1-289) expressed in E. Coli.
FCM (Flow Cytometry)1/200 - 1/400
Sequence
(AA: 227-382) expressed in E. Coli.
Catalog
31737
$341.00
-
+

Contact us to order

Images

Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Cell Culture Products

Figure 2: Western blot analysis using MAPK9 mAb against human MAPK9 (AA: 227-382) recombinant protein. (Expected MW is 44.4 kDa)

Cell Culture Products

Figure 3: Western blot analysis using MAPK9 mAb against HEK293 (1) and MAPK9 (AA: 227-382)-hIgGFc transfected HEK293 (2) cell lysate.

Cell Culture Products

Figure 4: Western blot analysis using MAPK9 mouse mAb against HEK293 (1) and U251 (2) cell lysate.

Cell Culture Products

Figure 5: Flow cytometric analysis of Hela cells using MAPK9 mouse mAb (green) and negative control (red).

Cell Culture Products
Tissue Array Results
Position Tissues Name Result Localization
Nucleus Cytoplasm Membrane
E9/10 Endometrial Cancer
View Full Documents
Product Overview
Description

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

References (references)
References (references) 1.Neuro Oncol. 2016 Jul;18(7):950-61.
2.Biochem Cell Biol. 2015 Dec;93(6):604-10.

Please view FAQs here