LHCGR Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesHHG; LHR; LCGR; LGR2; ULG5; LHRHR; LSH-R; LH/CGR; LH/CG-R
ProductOrderL
Clone#8G9A2
Entrez GenelD3973
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenLHR-29 from ATCC
MW78.6kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
human luteinizing hormone/human chorionic gonadotropin (LH/hCG) receptor, extracellular domain
Catalog#: 30751
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Images
Elisa
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western Blot
Figure 2: Western blot analysis using LHCGR mouse mAb against HepG2 (1), Jurkat (2), and SMMC-7721 (3) cell lysate.
Figure 2: Western blot analysis using LHCGR mouse mAb against HepG2 (1), Jurkat (2), and SMMC-7721 (3) cell lysate.
Immunofluorescence analysis
Figure 3:Immunofluorescence analysis of Hela cells using LHR-29 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Figure 3:Immunofluorescence analysis of Hela cells using LHR-29 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Flow cytometric
Figure 4: Flow cytometric analysis of Jurkat cells using LHCGR mouse mAb (green) and negative control (red).
Figure 4: Flow cytometric analysis of Jurkat cells using LHCGR mouse mAb (green) and negative control (red).
Product Overview
Description

This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.

References (references)
References (references)Cancer Res. 57: 857-864, 1997
Reprod Biol Endocrinol. 2011 May 15;9:64.