KRT19 Primary Antibody
|Aliases||K19; CK19; K1CS; MGC15366|
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Immunogen||Purified recombinant fragment of human KRT19 expressed in E. Coli. |
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|ICC (Immunocytochemistry)||1/200 - 1/1000|
|IHC_P(Immunohistochemistry)||1/200 - 1/1000|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using KRT19 mAb against human KRT19 (AA: 115-269) recombinant protein. (Expected MW is 43.1 kDa)
Figure 2: Western blot analysis using KRT19 mouse mAb against T47D (1), MCF-7 (2), HepG2 (3) and SW620 (4) cell lysate.
Figure 3: Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using KRT19 mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded human colon cancer tissues using KRT19 mouse mAb with DAB staining.
Figure 5: Immunohistochemical analysis of paraffin-embedded human stomach cancer tissues using KRT19 mouse mAb with DAB staining.
Figure 6: Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using KRT19 mouse mAb with DAB staining.
Figure 7: Immunofluorescence analysis of HepG2 cells using KRT19 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
|References (references)||1. Exp Cell Res. 2009 Jul 1;315(11):1964-74. |
2. Acta Cytol. 2008 Sep-Oct;52(5):541-8.