KHDRBS2 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesSLM1; SLM-1; bA535F17.1
ProductOrderK
Clone#3D12C11
Entrez GenelD202559
FormulationPurified antibody in PBS with 0.05% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human KHDRBS2 (AA: 160-349) expressed in E. Coli.
MW39kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Mouse
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
160-349
Catalog#: 30644
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Images
Western Blot
Figure 1: Western blot analysis using KHDRBS2 mAb against human KHDRBS2 (AA: 160-349) recombinant protein. (Expected MW is 46.3 kDa)
Figure 1: Western blot analysis using KHDRBS2 mAb against human KHDRBS2 (AA: 160-349) recombinant protein. (Expected MW is 46.3 kDa)
Western Blot
Figure 2: Western blot analysis using KHDRBS2 mouse mAb against K562 (1), HEK293 (2), NTERA-2 (3), Hela (4), HepG2 (5), Jurkat (6), A431 (7), NIH/3T3 (8) cell lysate.
Figure 2: Western blot analysis using KHDRBS2 mouse mAb against K562 (1), HEK293 (2), NTERA-2 (3), Hela (4), HepG2 (5), Jurkat (6), A431 (7), NIH/3T3 (8) cell lysate.
Flow cytometric
Figure 3: Flow cytometric analysis of K562 cells using KHDRBS2 mouse mAb (green) and negative control (red).
Figure 3: Flow cytometric analysis of K562 cells using KHDRBS2 mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity)

References (references)
References (references)1. Mol Biol Cell. 2003 Jan;14(1):274-87.
2.
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