JAK2 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesJTK10; THCYT3
ProductOrderJ
Clone#5C12C9
Entrez GenelD3717
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human JAK2 (AA: 745-955) expressed in E. Coli.
MW130.7kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
745-955
Catalog#: 30747
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Images
Western Blot
Figure 1: Western blot analysis using JAK2 mAb against human JAK2(AA: 745-955) recombinant protein. (Expected MW is 27.1 kDa)
Figure 1: Western blot analysis using JAK2 mAb against human JAK2(AA: 745-955) recombinant protein. (Expected MW is 27.1 kDa)
Western Blot
Figure 2: Western blot analysis using JAK2 mAb against HEK293 (1) and JAK2(AA: 545-1124)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using JAK2 mAb against HEK293 (1) and JAK2(AA: 545-1124)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 3: Flow cytometric analysis of Hela cells using JAK2 mouse mAb (green) and negative control (red).
Figure 3: Flow cytometric analysis of Hela cells using JAK2 mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 4: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using JAK2 mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using JAK2 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 5: Immunohistochemical analysis of paraffin-embedded breast cancer tissues using JAK2 mouse mAb with DAB staining.
Figure 5: Immunohistochemical analysis of paraffin-embedded breast cancer tissues using JAK2 mouse mAb with DAB staining.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

References (references)
References (references)Blood. 2014 May 1;123(18):2826-37.
PLoS One. 2013 May 24;8(5):e64628.