Mouse Monoclonal Antibody to IL1A

Item Information
Catalog #	Size/Concentration	Price
90003	100ug	$358.00

Specification
Aliases	IL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha
Clone#	6G4A5
Entrez GeneID	3552
Formulation	Purified antibody in PBS with 0.05% sodium azide
Host	Mouse
Isotype	IgG1
Immunogen	Purified recombinant fragment of human IL1A (AA: extra(155-354)) expressed in E. Coli.
MW	30.6kDa

Sequence
Extra (155-354

Images

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Figure 2:Western blot analysis using IL1A mAb against human IL1A (AA: 113-271) recombinant protein. (Expected MW is 44 kDa)

Figure 3:Flow cytometric analysis of Jurkat cells using IL1A mouse mAb (green) and negative control (red).

Figure 4:Flow cytometric analysis of MOLT4 cells using IL1A mouse mAb (green) and negative control (red).

Figure 5:Flow cytometric analysis of THP-1 cells using IL1A mouse mAb (green) and negative control (red).

Product Overview

Description	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

References (references)

References (references)	1,Noise Health. Mar-Apr 2019;21(99):77-82. 2,Crit Care. 2020 Jul 18;24(1):445.