Mouse Monoclonal Antibody to IL1A

Item Information
Catalog # Size/Concentration Price
90003 100ug $358.00
Specification
AliasesIL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha
Clone#6G4A5
Entrez GeneID3552
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human IL1A (AA: extra(155-354)) expressed in E. Coli.
MW30.6kDa
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
Extra (155-354
Catalog
90003

Contact us to order

Images

Elisa

Cell Culture Products

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Cell Culture Products

Figure 2:Western blot analysis using IL1A mAb against human IL1A (AA: 113-271) recombinant protein. (Expected MW is 44 kDa)

Flow cytometric analysis

Cell Culture Products

Figure 3:Flow cytometric analysis of Jurkat cells using IL1A mouse mAb (green) and negative control (red).

Flow cytometric analysis

Cell Culture Products

Figure 4:Flow cytometric analysis of MOLT4 cells using IL1A mouse mAb (green) and negative control (red).

Flow cytometric analysis

Cell Culture Products

Figure 5:Flow cytometric analysis of THP-1 cells using IL1A mouse mAb (green) and negative control (red).

Product Overview
Description

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

References (references)
References (references) 1,Noise Health. Mar-Apr 2019;21(99):77-82. 2,Crit Care. 2020 Jul 18;24(1):445.

Please view FAQs here