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Mouse Monoclonal Antibody to IL1A
Item Information | ||
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Catalog # | Size/Concentration | Price |
90003 | 100ug | $376.00 |
Specification | |
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Aliases | IL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha |
Clone# | 6G4A5 |
Entrez GeneID | 3552 |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Host | Mouse |
Isotype | IgG1 |
Immunogen | Purified recombinant fragment of human IL1A (AA: extra(155-354)) expressed in E. Coli. |
MW | 30.6kDa |
Application | |
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ELISA | 1/10000 |
FCM (Flow Cytometry) | 1/200 - 1/400 |
WB (Western Blot) | 1/500 - 1/2000 |
Sequence |
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Extra (155-354 |
Elisa

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot

Figure 2:Western blot analysis using IL1A mAb against human IL1A (AA: 113-271) recombinant protein. (Expected MW is 44 kDa)
Flow cytometric analysis

Figure 3:Flow cytometric analysis of Jurkat cells using IL1A mouse mAb (green) and negative control (red).
Flow cytometric analysis

Figure 4:Flow cytometric analysis of MOLT4 cells using IL1A mouse mAb (green) and negative control (red).
Flow cytometric analysis

Figure 5:Flow cytometric analysis of THP-1 cells using IL1A mouse mAb (green) and negative control (red).
Description | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. |
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References (references) | 1,Noise Health. Mar-Apr 2019;21(99):77-82. 2,Crit Care. 2020 Jul 18;24(1):445. |
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