IGFBP7 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesAGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1
ProductOrderI
Clone#5A4A9
Entrez GenelD3490
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human IGFBP7 (AA: 52-156) expressed in E. Coli.
MW29.1kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
52-156
Catalog#: 30564
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Images
Western Blot
Figure 1: Western blot analysis using IGFBP7 mAb against human IGFBP7 recombinant protein. (Expected MW is 36 kDa)
Figure 1: Western blot analysis using IGFBP7 mAb against human IGFBP7 recombinant protein. (Expected MW is 36 kDa)
Western Blot
Figure 2: Western blot analysis using IGFBP7 mAb against HEK293 (1) and IGFBP7 (AA: 52-156)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using IGFBP7 mAb against HEK293 (1) and IGFBP7 (AA: 52-156)-hIgGFc transfected HEK293 (2) cell lysate.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
DescriptionThis gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).
References (references)
References (references)1. Sci Signal. 2012 Dec 18;5(255):ra92.
2. Cancer Biol Ther. 2012 Feb 1;13(3):148-55.